While energy expenditure did not significantly differ between Npvf −/− and WT mice for both sexes ( Figure 4 Q,S), Npvf −/− mice exhibited an increase in HFD intake, although this increase did not reach statistical significance in females ( p = 0.06) ( Figure 4 R,T).
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0.0600
The sentences
Consistent with this reduced adiposity, weights across the white adipose tissue depots in female Npvf −/− mice dissected at 18 weeks of age were significantly reduced compared to female WT mice ( Figure 3 I, main effect of genotype F(1,9) = 7.32, p < 0.05), and the summed weights of these dissected white adipose tissue depots showed a strong trend towards decreasing ( Figure 3 J).