Barely Significant
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Sex-Specific Role of NPVF Signalling in Homeostatic Control.

Biomolecules · 2026 · PMC12937708 · PMID 41750301

2
hedged sentences
0.0600
closest p · 1.2× alpha
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boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)
While energy expenditure did not significantly differ between Npvf −/− and WT mice for both sexes ( Figure 4 Q,S), Npvf −/− mice exhibited an increase in HFD intake, although this increase did not reach statistical significance in females ( p = 0.06) ( Figure 4 R,T).

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a strong trendno p-value reported
Consistent with this reduced adiposity, weights across the white adipose tissue depots in female Npvf −/− mice dissected at 18 weeks of age were significantly reduced compared to female WT mice ( Figure 3 I, main effect of genotype F(1,9) = 7.32, p < 0.05), and the summed weights of these dissected white adipose tissue depots showed a strong trend towards decreasing ( Figure 3 J).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.