Immunohistochemical staining for F4/80 showed a trend toward increased positive areas in TSNO mice following CA supplementation, although the difference was not significant ( Figure S1A,B ).
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Strain-Dependent Effects of Dietary Cholic Acid on Liver Fibrogenesis and Gut Microbiota in TSNO and TSOD Mice.
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Vim , a mesenchymal marker, showed a tendency to increase in response to CA supplementation in both strains; however, these changes did not reach statistical significance.