Shelterin Component TPP1 Drives Tumor Progression and Predicts Poor Prognosis in Hepatocellular Carcinoma.

Biomedicines · 2026 · PMC12938003 · PMID 41751263

Europe PMC DOI

hedged sentences

0.1250

closest p · 2.5× alpha

0.1250

boldest claim

The sentences

did not reach statistical significancep = 0.125not close (p > 0.1)

In survival analysis, patients with high TPP1 expression exhibited a trend toward poorer overall survival, although this difference did not reach statistical significance ( p = 0.125; Figure 6 B).

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showed a trendno p-value reported

Tumors also showed a trend toward increased telomerase activity.

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