Obesity-associated gut microbiome influences diet-induced metabolic and cognitive outcomes in older adults.

Gut Microbes Rep · 2026 · PMC12938881 · PMID 41907517

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0760

boldest claim

The sentences

showed a trendp = 0.059so close (0.05 < p ≤ 0.1)

Among individuals with obesity, increases in Christensenellaceae_R-7_group abundance showed a trend with improved PSMT scores ( ρ = 0.584, p = 0.059) ( Figure 3f ).

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approached significancep = 0.076so close (0.05 < p ≤ 0.1)

Using Fisher’s exact test, the association approached significance ( p = 0.076).

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a possible trendno p-value reported

MCI status was not a significant predictor (B = 1.115, SE = 0.925, Wald = 1.456, p = .228), though the odds ratio (OR = 3.051, 95% CI [0.498, 18.680]) indicated a possible trend toward increased obesity risk among participants with MCI.

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