Flow Diversion vs. Coiling for Large and Giant Intracranial Aneurysms: A Systematic Review and Meta-Analysis.

J Clin Med · 2026 · PMC12942218 · PMID 41753045

Europe PMC DOI

hedged sentences

0.0004

closest p · 0.0× alpha

0.0571

boldest claim

The sentences

did not reach statistical significancep = 0.0004actually significant

While the moderator analysis did not reach statistical significance, subgroup analysis showed a significant difference in occlusion rates between FD and coiling (χ 2 = 12.59, p = 0.0004).

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showed a trendp = 0.0571so close (0.05 < p ≤ 0.1)

27%; p = 0.0001) and showed a trend toward a higher rate of complete occlusion ( p = 0.0571).

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narrowly missed statistical significancep = 0.0571so close (0.05 < p ≤ 0.1)

The pooled OR favored FD with an OR of 1.78 (95% CI: 0.98–3.24), although this trend narrowly missed statistical significance ( p = 0.0571).

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