Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening.

Exp Biol Med (Maywood) · 2026 · PMC12945842 · PMID 41767749

Europe PMC DOI

hedged sentences

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closest p · 1.6× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Other HLA class II types, including HLA-DRB1, HLA-DMA, HLA-DMB, HLA-DQA1, and HLA-DPA1, were also downregulated in the relapsed cohort relative to the relapse-free group; however, such differences did not reach statistical significance ( p = 0.08–0.15) ( Supplementary Figure S1 ).

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failed to reach statistical significanceno p-value reported

Although PVR was hypermethylated in the recurrence group compared to the non-recurrence group, it failed to reach statistical significance.

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