Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction.

While frailty trended toward being more prevalent in patients with elevated NT-proBNP compared with those with normal levels, this did not reach statistical significance (44.80% vs 30.91%, chi-square = 3.06; P = 0.080) ( Figure 2E ).

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Unintentional weight loss showed a trend to be more prevalent in patients with higher PCWP ( Figure 3C ), muscle weakness showed a trend to be more prevalent in patients with higher chronic kidney disease stage ( Figure 3D ), and muscle weakness and unintentional weight loss showed a trend for increase in the subgroup of patients with high NT-proBNP compared with those with low NT-proBNP levels ( Figure 3E ); however, these did not reach statistical significance.

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