Barely Significant
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Impact of serum progesterone levels and rescue progesterone supplemental luteal support on pregnancy outcomes in frozen embryo transfer: a controlled trial.

BMC Pregnancy Childbirth · 2026 · PMC12955326 · PMID 41622134

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Although numerical differences were noted, particularly with slightly higher pregnancy rates in Groups I and II compared with Group III, these did not reach statistical significance (Table 2 ).

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approached significanceno p-value reported
Estradiol ( p = .083) and BMI ( p = .107) approached significance but did not reach the threshold.

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a numerical trendno p-value reported
Similarly, the lack of significant difference in pregnancy loss, despite a numerical trend, indicates that low progesterone might not be as critical a driver of early miscarriage in all patients as previously hypothesized.

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