Tonsil-derived mesenchymal stem cells alleviate skin inflammation by modulating neutrophil extracellular trap formation and T cell migration.

In the DNCB + T-MSC group, the medullary sinus area showed a further increase (7.73 ± 2.91%) relative to the DNCB group; however, this difference did not reach statistical significance.

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Overall, expression of activation and adhesion markers on LN CD4 + T cells showed a trend toward recovery following T-MSC administration in DNCB-treated mice, although these changes did not reach statistical significance ( Fig 5E ).

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