Prognostic relevance of specific TIL (CD4+, CD8+, and FOXP3 + T-cell infiltrates) in triple-negative breast cancer: short- and long-term outcomes.

Breast Cancer · 2026 · PMC12960379 · PMID 41498919

Europe PMC DOI

hedged sentences

0.0773

closest p · 1.5× alpha

0.0773

boldest claim

The sentences

near-significantp = 0.0773so close (0.05 < p ≤ 0.1)

We observed a near-significant ( p = 0.0773) increase in CD4 + T cells in cases with pCR comparing with cases without pCR, while no significant differences ( p = 0.3129) were found in the frequency of CD8 + T cells between groups.

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did not reach statistical significanceno p-value reported

5 C and D ) showed trends toward improved DFS ( p = 0.4126 and p = 0.1375 , respectively) , but these differences did not reach statistical significance.

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marginally significantno p-value reported

Additionally, while not statistically significant ( p = 0.0667), the percentage of CD 8 + T cells showed a marginally significant association with negative axillary lymph nodes.

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