Integrin αvβ3-dependent pathogenic effect and therapeutic effects of DL-N2 combined with EGFR inhibitors in pancreatic adenocarcinoma.

J Transl Med · 2026 · PMC12961825 · PMID 41742226

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

a negative trendp = 0.065so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)

Survival analysis revealed that high ITGAV expression was significantly associated with poor overall survival ( p = 0.031), while ITGB3 showed a negative trend that did not reach statistical significance ( p = 0.065) (Fig. 1 C–D).

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