Connective tissue growth factor contributes to resistance to anti-angiogenic therapies in renal cancer.

Theranostics · 2026 · PMC12964018 · PMID 41799185

Europe PMC DOI

hedged sentence

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

showed a trendP = 0.13not close (p > 0.1)

did not reach statistical significanceno p-value reported

Although patients with VEGFC levels above the optimal cutoff of 23.471 pg/mL showed a trend toward shorter PFS (hazard ratio: 1.4 [0.73-2.7], P = 0.13; Figure S7 A-B ), this association did not reach statistical significance.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.