Association between "Life's Critical 9" health score and the risk of inflammatory bowel disease: a prospective cohort study from the UK biobank.

BMC Public Health · 2026 · PMC12964813 · PMID 41639836

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP = 0.059so close (0.05 < p ≤ 0.1)

While LC9 demonstrated a significant protective effect against UC (HR = 0.909, 95% CI: 0.863–0.958 in Model 3), the association with CD did not reach statistical significance in the fully adjusted model (HR = 0.928, 95% CI: 0.858–1.003, P = 0.059).

also in 111,027 other papers

borderline non-significantP = 0.060so close (0.05 < p ≤ 0.1)

For overall IBD, the continuous LC9 score was significantly associated with reduced IBD risk in Models 1 and 2 (Model 1: HR 0.956, 95% CI 0.934–0.979, P < 0.001; Model 2: HR 0.960, 95% CI 0.937–0.983, P = 0.001), while the association in Model 3 was attenuated and borderline non-significant (HR 0.976, 95% CI 0.953–1.001, P = 0.060).

also in 434 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.