The prognostic impact of myeloid co-mutation burden in TP53-mutated AML/MDS after allogeneic stem cell transplantation: a multicenter retrospective analysis.

Ann Hematol · 2026 · PMC12967432 · PMID 41793509

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Complex karyotype showed a trend toward inferior outcomes (3-y OS: 37.5% vs. 65.1%, p = 0.08, 3-y PFS: 31.3% vs. 54.2%, p = 0.08).

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a negative trendno p-value reported

Age > 50 years adversely affected PFS, and complex karyotype showed a negative trend.

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