Exploratory pilot trial of astaxanthin supplementation in PCOS patients at risk of OHSS with focus on RAGE-NFκB pathway.

Sci Rep · 2026 · PMC12972036 · PMID 41673418

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.2200

boldest claim

The sentences

a near-significant trendp = 0.066so close (0.05 < p ≤ 0.1)

Endocrine profiles measured on days 1–3 of the menstrual cycle (including AMH, FSH, LH, Estradiol, progesterone, TSH, prolactin, and fasting blood sugar) did not reveal any significant intergroup differences, although there was a near-significant trend in LH levels ( p = 0.066).

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did not reach statistical significancep = 0.220not close (p > 0.1)

Although the categorization of total retrieved oocytes (< 20, 20–30, or > 30) revealed a slight numerical difference (with the proportion of cycles yielding < 20 oocytes tending to be higher in the placebo group), this did not reach statistical significance ( p = 0.220).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.