Repeated (Weekly) Intra-Articular Injections of Sulfated Galactans Attenuate Cartilage Degeneration in a Rat Model of Osteoarthritis.

HA and SG‐treated groups displayed partial restoration of type II collagen distribution, although the difference did not reach statistical significance compared with OA controls (Figure 7K ).

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The SG 500 μg group showed a trend toward higher type II collagen staining than OA + NSS. 3.5 SG Reduces IL‐1β‐Induced Extracellular Matrix Degradation and Promotes Matrix Synthesis in C28/I2 Chondrocytes C28/I2 human chondrocytes were stimulated with IL‐1β (10 ng/mL) for 12 h to induce an inflammatory response.

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