Leveraging patient data to detect systematic shifts in daptomycin susceptibility testing associated with reduced prescribing.

Daptomycin susceptibility rates at HUP exhibited a similar trend where susceptibility rates decreased in the affected epoch before rebounding in the recovery epoch; however, these changes did not reach statistical significance.

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In contrast, the lack of a significant trend in the clinical data suggests, or the absence of a corresponding QC shift suggests no meaningful loss of process control (end-of-process).

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