Development of a Dual-Drug-Loaded Bone Cement with Osteogenic Potential and Antibiotic Release.

It is important to note that while numerical differences were observedfor example, ICA extracts showing values slightly above SI at equivalent loadings, and dual-drug systems showing values above some single-agent groupsbut these differences did not reach statistical significance under the tested conditions.

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Upon drug incorporation, a clear trend of increased matrix porosity and a more open, looser crystal packing is evident.

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