Patients with persistent atrial fibrillation and metabolic comorbidities have an altered inflammatory state of atrial epicardial adipose tissue, which is linked to CT-attenuation.

Cardiovasc Diabetol · 2025 · PMC12980984 · PMID 41454313

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closest p · 1.2× alpha

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The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

Diabetic AF patients (9/134) showed a trend towards a larger atrial CT-EAT-volume versus non-diabetics 17.9 ± 7.9 versus 15.5 ± 7.2 ml/m 2 , ( p = 0.07), respectively, a significantly lower atrial CT-EAT-attenuation, − 76.5 ± 5.2 versus − 73.2 ± 4.7HU, ( p = 0.05) and a strong trend towards increased CD68 macrophages 174.9[301.8] versus 102.8[132.3] cells/mm 2 , p = 0.06.

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Hypertensive AF patients (60/134) showed a trend towards a larger atrial CT-EAT-volume than non-hypertensive patients, 17.0 ± 7.6 versus 14.6 ± 6.7 ml/m 2 ( p = 0.06), and towards lower atrial CT-EAT-attenuation − 74.2 ± 5.3 versus − 72.8 ± 4.4HU, ( p = 0.10), respectively.

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