Kaplan–Meier survival analysis indicated a trend toward shorter OS in patients with high DCTPP1 expression, although this did not reach statistical significance (Fig. 11 C).
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DCTPP1 drives immunosuppression and poor prognosis in breast cancer by promoting M2 macrophage polarization.
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Notably, positive DCTPP1 expression in tumor parenchyma (CK+DCTPP1+) showed a trend toward worse OS, although this did not reach statistical significance ( P = 0.091, HR = 3.416, 95% CI: 0.822–14.188).