TCGA-Informed Spatial Profiling Reveals Peripheral CD147 Expression at the Invasive Tumor Front as a Prognostic Indicator in OSCC.

Int J Mol Sci · 2026 · PMC12985257 · PMID 41828399

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

near-significantp = 0.062so close (0.05 < p ≤ 0.1)

While vascular invasion displayed a near-significant difference (Mann–Whitney U test, p = 0.062), no correlation was found with UICC stage, nodal status, grading, or recurrence ( Table 2 ).

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did not reach statistical significanceno p-value reported

These findings suggest that while CD147 expression may exhibit a mild increase with advancing local tumor extent, the overall relationship between CD147 immunoscore and tumor stage did not reach statistical significance.

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