A Clinicopathologic, Molecular, and Prognostic Comparison Between Early- and Late-Onset Colorectal Cancer in Korea: A Single-Center Retrospective Cohort Study.

J Clin Med · 2026 · PMC12986117 · PMID 41827154

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0870

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

47.1%); however, this difference did not reach statistical significance ( p = 0.059).

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showed a trendp = 0.087so close (0.05 < p ≤ 0.1)

Compared with AJCC stage I, stage III showed a trend toward higher mortality (HR 1.74, 95% CI: 0.92–3.29; p = 0.087), and stage IV was strongly associated with worse survival (HR 7.17, 95% CI: 3.84–13.38; p < 0.001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.