Evaluation of Therapeutic Effects and Underlying Mechanisms of Baichuan Baile Formula in Rodent Insomnia Models.

Although a trend toward reduced NREM sleep fragmentation was observed in both groups, this effect did not reach statistical significance ( Figure 4 C).

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Behaviorally, BCBL-treated mice showed a trend toward better performance in memory tests (Y-maze and novel object recognition).

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Regarding the reduction in the number of awakenings, the diazepam group showed a statistically significant difference compared to the model group, whereas the high-dose BCBL group exhibited a decreasing trend that did not reach statistical significance.

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