Barely Significant
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Parameter-Specific Effects of Low-Intensity Transcranial Focused Ultrasound Stimulation on Depression-Like Behaviors in a CUMS Mouse Model.

Neuropsychiatr Dis Treat · 2026 · PMC12991375 · PMID 41847603

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36 In our study, although post-hoc pairwise comparisons did not reach statistical significance, the data present a consistent pattern.

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showed a trendno p-value reported
Third, while LIFUS2 yielded significant behavioral effects and showed a trend toward gut microbiota changes, the precise neurobiological mechanisms underlying these effects are not yet fully understood and require further study.

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