Distinct Proteomic and Glycosylation Signatures Differentiate A549 Tumor and BEAS-2B Nontumor Cell Line-Derived Small Extracellular Vesicles.

Mol Cell Proteomics · 2026 · PMC12992954 · PMID 41644049

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a nonsignificant trendno p-value reported

In addition, a nonsignificant trend toward higher levels of fucosylation in A549 sEVs (FC = 1.14) was observed, whereas sialylation showed a modest, nonsignificant decrease (FC = 0.97).

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

In our study, A549 sEVs showed a trend toward increased fucosylation compared with BEAS-2B sEVs, although this difference did not reach statistical significance.

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