showed a trendp = 0.1388
The median age of participants in these trials ranged from 62 years to 78.5 years and showed a trend upwards over time ( p = 0.1388).
The median age of participants in these trials ranged from 62 years to 78.5 years and showed a trend upwards over time ( p = 0.1388).
A weighted linear regression, accounting for study sample size, estimated an average annual increase in median age of 0.09 years (95% CI: −0.06 to 0.24, p = 0.236); this trend also did not reach statistical significance (Figure 2 ).