Stride-level measurement of gait as an early sensitive marker of disability progression in ambulatory patients with multiple sclerosis.

In a post-hoc analysis, the correlations between changes in MSWS-12 and SV95C did not reach statistical significance in the overall population (R = −0·27, p = 0·07, n = 47), nor in the PMS (R = −0·29, p = 0·31, n = 14) or RRMS (R = −0·24, p = 0·18, n = 33) subpopulations.

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Introduction Over recent years, a clear trend towards the use of wearable technologies has emerged across many neurological conditions. 1 Digital outcomes allow objective, continuous, and precise quantification of disease progression. 2 The higher temporal resolution and real-world relevance of digital outcomes potentially provide significant advantages over conventional assessments, which are often limited to periodic in-clinic visits and subjective evaluations.

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