Anticoagulant-free preparation of autologous platelet-rich plasma (PRP) / fluid platelet-rich fibrin (f-PRF): a pre-clinical comparative performance study.

Front Pharmacol · 2026 · PMC12997048 · PMID 41859336

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showed a trendno p-value reported

Although ExprecellTM showed a trend toward higher platelet-derived EVs (80% vs. 69%), both preparations preserved physiologically relevant EV populations possibly associated with regenerative, hemostatic and inflammatory properties, although further studies are needed.

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did not reach statistical significanceno p-value reported

However, these differences did not reach statistical significance ( Figures 6B–D ).

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