Subcortical microstructural impairment in amyotrophic lateral sclerosis: clinical correlates of neurite orientation dispersion and density imaging (NODDI) changes.

Front Neurosci · 2026 · PMC12997300 · PMID 41859232

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

a negative trendp = 0.057so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.057so close (0.05 < p ≤ 0.1)

Although a negative trend was consistently observed, it did not reach statistical significance in either regression model (OLS: R 2 = 0.16, p = 0.057; robust: R 2 = 0.25, p = 0.059).

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