Barely Significant
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Real-world outcomes of encorafenib, cetuximab ± binimetinib for BRAF‑mutated metastatic colorectal cancer: the BEETS (JACCRO CC‑18) study.

Oncologist · 2026 · PMC13006056 · PMID 41761577

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Although the difference did not reach statistical significance, OS tended to be more favorable in the triplet cohort.

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showed a trendno p-value reported
Three drugs, triplet therapy showed a trend toward improved survival in patients with poor prognostic factors, suggesting a potential role for risk-adapted regimen selection.

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