Integrating chronic inflammation and hypoxia: the potential role of HIF-1α in tumor behavior and therapy response in high-grade serous ovarian cancer.

Increased peritoneal HIF-1α at baseline showed a trend toward shorter progression-free survival.

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Kaplan–Meier analysis demonstrated a clear separation between groups, though the difference did not reach statistical significance and Cox regression suggested a more than threefold increased risk of chemoresistance.

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