showed a trendP = 0.058
In a sub-analysis restricted to paroxysmal AF patients, pre-procedural time spent in AF showed a trend toward an association with AF recurrence (HR 1.08 per 10% increase, 95% CI 1.00–1.18, P = 0.058); this model was adjusted for age, sex, chronic obstructive pulmonary disease, diabetes mellitus, and thyroid dysfunction (see Supplementary material online , Table S3 ).