Long-term outcomes of external beam radiotherapy combined with high-dose-rate brachytherapy boost in intermediate- and high-risk prostate cancer.

Front Oncol · 2026 · PMC13008632 · PMID 41883962

Europe PMC DOI

hedged sentences

0.0790

closest p · 1.6× alpha

0.0950

boldest claim

The sentences

did not reach statistical significancep = 0.079so close (0.05 < p ≤ 0.1)

A trend toward improved LC was observed in patients receiving ADT; however, this difference did not reach statistical significance (log-rank χ2 = 3.077, df = 1, p = 0.079).

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a strong trendp=0.095so close (0.05 < p ≤ 0.1)

In our univariate analysis, a positive PSMA-PET scan showed a strong trend toward being a predictor for worse LC (HR = 6.94, p=0.095), though it was not statistically significant, again likely due to low event rates.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.