Comparative Analysis of Cardiac Puncture and Perfusate Blood Collection for Murine Extracellular Vesicle Isolation.

However, when accounting for the total plasma volume obtained by each method (cardiac puncture: ~0.5 mL; perfusate: ~3 mL), total particle yield per animal showed a trend toward higher recovery with perfusate blood collection in both naïve and 50 kdyne SCI groups, though these differences did not reach statistical significance ( Figure 2 c,d). 3.2.

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