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HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation.

PLoS One · 2026 · PMC13012508 · PMID 41875183

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showed a trendno p-value reported
Analysis of the GEPIA database indicated that elevated levels of both genes showed a trend toward association with poor patient prognosis, although this did not reach statistical significance.

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