Continuous administration of heparin during free flap surgery for head and neck tumors reduces the risk of pulmonary embolism.

Oral Maxillofac Surg · 2026 · PMC13013164 · PMID 41876767

Europe PMC DOI

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a clear trendno p-value reported

Although these results did not reach statistical significance, they showed a clear trend.

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did not reach statistical significanceno p-value reported

However, the incidence of postoperative bleeding requiring surgical intervention increased from 4.3% to 13%, although this change did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.