Efficacy and safety of sequential immunotherapy following concurrent radiotherapy with S-1 in older patients with esophageal squamous cell carcinoma: an inverse probability weighting analysis.

Front Immunol · 2026 · PMC13013532 · PMID 41890746

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep=0.053so close (0.05 < p ≤ 0.1)

A lower incidence of vomiting was also observed in the CCRT+ICIs group, although the difference did not reach statistical significance (p=0.053).

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a strong trendno p-value reported

The IPTW-adjusted analysis confirms a strong trend favoring the CCRT+ICIs strategy at the group level.

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