Selenium Supplementation in Graves' Orbitopathy: Effects on Blood Concentrations and Clinical Outcomes.

Clin Ophthalmol · 2026 · PMC13016390 · PMID 41891094

Europe PMC DOI

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0.1600

closest p · 3.2× alpha

0.1600

boldest claim

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did not reach statistical significanceP=0.16not close (p > 0.1)

The mean visual functioning subscale score improved from 54.69 ± 30.33 to 61.81 ± 29.08, but the difference did not reach statistical significance (mean difference: 7.12 ± 30.00; 95% CI: −3.03–17.27, P=0.16).

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showed a trendno p-value reported

11 , 19 The visual function subscale showed a trend toward improvement, but the change did not reach statistical significance, similar to findings in a Thai population, 21 possibly due to the low baseline CAS and relatively inactive disease status of most participants.

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