The Degeneration Paradox: Severely Degenerated Cervical Nucleus Pulposus Cells Display Enhanced Mechanoplasticity Under Moderate Cyclic Tensile Strain.

Biomolecules · 2026 · PMC13024720 · PMID 41897396

Europe PMC DOI

hedged sentences

0.0008

closest p · 0.0× alpha

0.0516

boldest claim

The sentences

highly significantp = 0.0008actually significant

Concurrently, a highly significant inverse correlation was observed between ROM and degeneration severity (W = 34.22, p = 0.0008).

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marginally significantp = 0.0516so close (0.05 < p ≤ 0.1)

While the global variance across all three Miyazaki grades (Welch’s ANOVA) exhibited a strong but marginally significant trend (W = 6.308, p = 0.0516), this is mathematically attributable to the restricted sample size of the Mild cohort ( n = 3), which diluted the omnibus statistical power.

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did not reach statistical significancep = 0.0988so close (0.05 < p ≤ 0.1)

a strong trendno p-value reported

Specifically, Dunn’s multiple comparisons test indicated that while the height loss score in the Severe group (2.700 ± 0) was numerically higher than that of the Mild group (1.667 ± 0.471), this pairwise comparison showed a strong trend but did not reach statistical significance (adjusted p = 0.0988), likely due to the conservative nature of the non-parametric test and the limited sample size in the Mild cohort.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.