Associations of the density of cells positive for neuropilin-1 (NRP1) with patient survival in the authors’ own cohort failed to reach statistical significance, likely because of the small sample size (39 patients), although there was a clear trend towards an association between high NRP1+ cell content and poorer survival in the sonic hedgehog (SHH) and non-Wingless (WNT)/SHH MB subgroups.
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Comment on Santana-Bejarano et al. NRP1 and GFAP Expression in the Medulloblastoma Microenvironment: Implications for Angiogenesis and Tumor Progression. <i>Cancers</i> 2025, <i>17,</i> 2417.
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