Antegrade Continence Enema Approaches: Outcomes, Lessons Learned and Overall Burden in a Mixed Urban-Rural Population.

Children (Basel) · 2026 · PMC13025410 · PMID 41897041

Europe PMC DOI

hedged sentences

0.1070

closest p · 2.1× alpha

0.1100

boldest claim

The sentences

did not reach statistical significancep = 0.107not close (p > 0.1)

On average, MACE was associated with substantially higher charges (USD 114,792) compared with LC (USD 47,478), though this difference did not reach statistical significance ( p = 0.107).

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failed to reach statistical significancep = 0.11not close (p > 0.1)

Although the difference in average charges failed to reach statistical significance ( p = 0.11) due to a relatively low sample size and variability within the dataset, costs in patients who underwent MACE were roughly three times higher, suggesting clinical and financial significance to children and their families.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.