Can Tc-99m-PSMA SPECT/CT Be Used as Accessible Alternative for Diagnosis of Biochemically Recurrent Prostate Cancer? A Prospective Study.

Diagnostics (Basel) · 2026 · PMC13025446 · PMID 41897628

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.3200

boldest claim

The sentences

showed a trendp = 0.058so close (0.05 < p ≤ 0.1)

ISUP grade per 1-grade increase showed a trend towards Tc-99m-PSMA SPECT/CT positivity (OR 1.67 per 1-grade increase, 95% CI 0.98–2.82; p = 0.058).

also in 53,322 other papers

did not reach statistical significancep = 0.32not close (p > 0.1)

In the univariate logistic regression, each PSA doubling was significantly associated with Tc-99m-PSMA SPECT/CT positivity (OR 2.87 per PSA doubling, 95% CI 1.07–7.71; p = 0.036) and with metastatic disease spread (OR 2.32 per PSA doubling, 95% CI 1.10–4.86; p = 0.026), while ISUP grade per 1-grade increase did not reach statistical significance for Tc-99m-PSMA SPECT/CT positivity ( p = 0.32) or metastatic disease spread ( p = 0.77).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.