Barely Significant
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Evidence on SGLT2 Inhibitors' Efficacy in Older and Frail Patients.

J Clin Med · 2026 · PMC13027104 · PMID 41899142

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showed a trendno p-value reported
The study also showed a trend towards a reduction in muscle mass, skeletal muscle mass, lean body mass, bone mineral content and handgrip strength; however, these findings did not reach statistical significance [ 12 ].

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