Fecal Microbiota Transplantation from APP/PS1 Mice Induces Th17-Related Inflammatory Parameters and Pathological Changes in the Gut-Brain Axis of Healthy C57BL/6J Mice.

Int J Mol Sci · 2026 · PMC13027225 · PMID 41898651

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0500

boldest claim

The sentences

highly significantp < 0.01actually significant

Additionally, Muribaculum exhibited a highly significant negative correlation with ileal IL-17A ( p < 0.01) and a significant negative correlation with hippocampal RORγt ( p < 0.05).

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did not reach statistical significancep > 0.05actually significant

These plots indicate a trend toward higher microbial α-diversity in Group M than in Group C, although the difference did not reach statistical significance ( p > 0.05). β-diversity analysis ( Figure 3 C) was performed to evaluate microbial community composition differences between groups.

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showed a trendno p-value reported

In the ordination plot, samples from Group C and Group M showed a trend of differential distribution along the coordinate axes.

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