Barely Significant
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The Effect of HER3 Expression on Prognosis in EGFR-Mutant Non-Small Cell Lung Cancer: A Retrospective Real-World Study.

Medicina (Kaunas) · 2026 · PMC13028177 · PMID 41901620

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a numerical trendno p-value reported
When overall survival data are evaluated, a numerical trend toward shorter survival times in the HER3-positive group was observed, consistent with the literature, though statistical significance was not reached.

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7.1 months; p = 0.285); however, this difference did not reach statistical significance and should be interpreted with caution given the small sample size.

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showed a trendno p-value reported
14.2 months), whereas those receiving TKI in the second line showed a trend toward longer OS in HER3-positive patients (20.5 vs. 17.2 months).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.