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Growth Hormone-Releasing Peptide-6 (GHRP-6) Ameliorates Post-Infarct Ventricular Remodeling and Systolic Dysfunction in a Model of Permanent Coronary Ligation.

Pharmaceuticals (Basel) · 2026 · PMC13029777 · PMID 41901314

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a strong trendno p-value reported
Notably, although limited by sample size ( p = 0.0614), a strong trend towards reduced mortality (10% versus 40% in controls) was observed, suggesting a potential survival benefit.

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Post-infarct myocardial interstitial fibrosis measurements using collagen-specific staining indicate that GHRP-6 intervention reduced tissue injury and the consequent scarring, although these differences did not reach statistical significance ( Figure 5 E).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.