Barely Significant
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Circulating and Respiratory Biomarkers in Sepsis-Induced ARDS: Diagnostic and Prognostic Insights - A Narrative Review.

J Inflamm Res · 2026 · PMC13033304 · PMID 41913792

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showed a trendno p-value reported
ARDS patients showed a trend of elevated sRAGE and SP-D levels, indicating epithelial damage in sepsis-induced ARDS.

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a significant trendno p-value reported
Elevated plasma Ang-2 is independently linked to a higher mortality risk, with a significant trend noted from days 1 to 3, particularly among pediatric hematopoietic stem cell transplant patients, highlighting ongoing endothelial injury ( Table 2 ). 314 Fluctuations in Ang-2 levels over time show varying relationships depending on assessment dates, with serial evaluations failing to effectively distinguish ARDS from non-ARDS conditions, thus limiting the reliability of a single measurement for diagnostics.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.