Genetic study identifies novel genes in developmental dysplasia of the hip.

Gene set enrichment analyses demonstrated nominally significant enrichment in the set related to collagen type XI trimer ( P = 4.18 × 10 −5 ) (Table S7 ).

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Aside from SLC38A4 , showing the significant signal in Japanese DDH, we found additional four signals, namely, LTBP1 , BOK , ERC2 and ITGA2 , all of which did not reach statistical significance in GO hip-OA GWAS alone (Fig. 4 , Fig.

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