Interestingly, total IgE was higher in coinfected children and malaria-specific IgE responses in the coinfected children showed a trend of negative association with P. falciparum parasite density, with IgE to α-gal and MSP3 having a statistically significant negative correlation with parasitemia, even though the levels of antigen-specific IgE responses were not significantly increased in this study group.
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Helminth coinfections mitigate clinical, parasitological, and immune outcomes in Mozambican children with malaria.
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S1c), coinfection was still associated with a decrease in body temperature, but it did not reach statistical significance (Additional file 1: Fig.