Effect of Liver Metastases on Survival in Microsatellite-Stable Metastatic Colorectal Cancer Treated with Immune Checkpoint Inhibitors.

Cancer Res Commun · 2026 · PMC13038315 · PMID 41615712

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Although this association did not reach statistical significance, likely because of the small sample size ( N = 7), none of these patients experienced liver progression during ICI therapies.

also in 111,027 other papers

showed a trendno p-value reported

In LEAP-017, patients without liver metastases showed a trend toward improved OS (HR, 0.65; 95% CI, 0.42–0.99), whereas those with liver metastases derived minimal benefit (HR, 0.91; 95% CI, 0.72–1.15; ref. 25 ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.